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Pt notes significant opioid induced constipation and discomfort. Pt has failed OTC medications including Miralax, Colace, Senokot, fiber, magnesium citrate and is at risk for severe constipation which could lead to bowel obstrucion. Requesting for relistor specifically to help restore normal bowel function by addressing the constipating effects of opioids directly. Other OlC meds such as lubiprostone, a chloride channel activator, is not a peripherally acting MU opioid receptor antagonist like Relistor. It does not directly address the effects the opioid has at the MU receptor and causes severe nausea. It does not give back normal bowel function due to OlC, Provider refuses to prescribe Lactolose as it is off label use and has minimal benefit for the patient, Prefer Relistor due to no drug-drug interactions with other medications as patient is taking multiple medications. There is real concern in the use of movantik and symproic and the impact on their effectiveness from other drugs patient is taking. This is for the best interest of the patient.
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addiction follow up
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Absorbine® (#10204) Bigeloil® Liquid Gel
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